Volunteers needed for clinical trials

Hundreds of clinical trials are currently underway at key research centers throughout California, many of which are having trouble recruiting patients. Among the trials that need more volunteers:

Smallpox vaccine test: Researchers at Stanford University Medical Center and Kaiser Permanente in Oakland are conducting a clinical trial to test whether diluted doses of the smallpox vaccine produce adequate immunity in adults who have previously been vaccinated. People interested in volunteering should call (650) 498-7423. Kaiser members should call (866) 604-1266.

Ovarian cancer drug: The City of Hope Cancer Center in Duarte is conducting a test of a new and relatively nontoxic drug, fenretinide, which is derived from vitamin A. Researchers are seeking ovarian cancer sufferers who have had only one prior chemotherapy program for their cancer, and whose cancer recurred after treatment. Interested patients should call (626) 359-8111. Ask to be connected with the admitting referral office.

Understanding how people recover from mania in bipolar illness: Scientists at the UCLA Mood Disorders Research Program in Westwood are seeking individuals with bipolar disorder, type 1, between the ages of 18 and 65. Contact Joni Zuckerbrow-Miller for more information: (310) 794-9913.