It took a while for David Duchovny to hit his professional stride after leaving “The X-Files” in 2002. He had small parts in a few television shows and movies (as Carrie’s ex-boyfriend in “Sex and the City” and as a hand model in “Zoolander,” most famously); he lent his voice to a few video games; and he starred in some films -- “Return to Me,” “The TV Set” and “Things We Lost in the Fire.” Then in 2007 he won a Golden Globe for best actor in a television comedy or musical for his starring role in Showtime’s “Californication.” (Myung J. Chun / Los Angeles Times)
Anderson has narrated several documentaries on scientific topics—a handy way to trade on Scully’s science background. In 2005 she played Lady Dedlock in a BBC adaptation of Charles Dickens’ “Bleak House” and was nominated for a BAFTA for best actress in a television series. Most recently she was tapped to host PBS’ Masterpiece Theater. (Lori Shepler / Los Angeles Times)
Robert Patrick (John Doggett)
A member of the “X-Files†family for only the final two seasons, Patrick has since gone on to play Johnny Cash’s abusive dad in “Walk the Line,†Marshall University’s head coach in “We are Marshall†and Col. Tom Ryan (center) in the television series “The Unit.†(Anne Cusack / Los Angeles Times)
Chris Carter
Upon the conclusion of the “X-Files†series in 2002, Carter went into a period of little activity. Though he’s been working on the “X-Files†sequel during that time, he also told Entertainment Weekly that he’s watched less TV in the years since “The X-Files†ended than he has in his entire life. Guess he was just enjoying some time off. (Ken Hively / Los Angeles Times)